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Bitter melon, also known as bitter gourd, Karela, or Balsam Pear, is a unique vegetable-fruit that can be used as food or medicine. It is considered the most bitter among all fruits and vegetables. Fresh bitter melon is a great course of Vitamin C, one of the most powerful natural antioxidants. Bitter melon notably contains the phytonutrient polypeptide-P, a plant insulin thought to lower blood sugar levels.